Development of the India COVID-19 vaccine tracker.

COVID-19 was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Since then, efforts were initiated to develop safe and effective vaccines. Till date, 11 vaccines have been included in the WHO's emergency use list. The emergence and spread of variant strains of SARS-CoV-2 has altered the disease transmission dynamics, thus creating a need for continuously monitoring the real-world effectiveness of various vaccines and assessing their overall impact on disease control. To achieve this goal, the Indian Council of Medical Research (ICMR) along with the Ministry of Health and Family Welfare, Government of India, took the lead to develop the India COVID-19 Vaccination Tracker by synergizing three different public health databases: National COVID-19 testing database, CoWIN vaccination database and the COVID-19 India portal. A Vaccine Data Analytics Committee (VDAC) was constituted to advise on various modalities of the proposed tracker. The VDAC reviewed the data related to COVID-19 testing, vaccination and patient outcomes available in the three databases and selected relevant data points for inclusion in the tracker, following which databases were integrated, using common identifiers, wherever feasible. Multiple data filters were applied to retrieve information of all individuals ≥18 yr who died after the acquisition of COVID-19 infection with or without vaccination, irrespective of the time between vaccination and test positivity. Vaccine effectiveness (VE) against the reduction of mortality and hospitalizations was initially assessed. As compared to the hospitalization data, mortality reporting was found to be much better in terms of correctness and completeness. Therefore, hospitalization data were not considered for analysis and presentation in the vaccine tracker. The vaccine tracker thus depicts VE against mortality, calculated by a cohort approach using person-time analysis. Incidence of COVID-19 deaths among one- and two-dose vaccine recipients was compared with that among unvaccinated groups, to estimate the rate ratios (RRs). VE was estimated as 96.6 and 97.5 per cent, with one and two doses of the vaccines, respectively, during the period of reporting. The India COVID-19 Vaccination Tracker was officially launched on September 9, 2021. The high VE against mortality, as demonstrated by the tracker, has helped aid in allaying vaccine hesitancy, augmenting and maintaining the momentum of India's COVID-19 vaccination drive.

Experiences and challenges faced by the working population during COVID-19 Lockdown: A qualitative study.

Background: The largest COVID-19 national lockdown was declared on 25 March 2020 in India with a total shutdown of workplaces and transport sectors. A complete lockdown deemed the entire population of the country to stay wherever they were residing at that point of time with no entry or exit movements being permitted thereafter. This unique situation betwixt a menacing health crisis rolled out a scenario uncustomary to the nation`s citizens. The varied responses of the masses to the lockdown need to be captured in order to understand the difficulties and dilemmas faced by them. Hence, this qualitative analysis aimed to capture the immediate challenges and experiences faced by the working population during the first-ever declared nationwide lockdown. Methodology: After obtaining institutional ethical committee clearance, a qualitative study was conducted using grounded theory approach. Using purposive sampling, people representative of the working-class population in Kerala were selected from three districts of the state. Equal representation of males and females were maintained. In-depth interviews were conducted via telephone using an interview guide till data saturation was obtained. The audio recorded data were later transcribed verbatim and translated to English. The transcripts were then manually coded to identify the emerging themes and subthemes and conclusions were drawn after triangulation. Results: The age of the study participants ranged from 32 to 71 years, they were occupied in different vocations and belonged to middle-class families across three districts of Kerala. All of them were aware and were mentally prepared for a national lockdown. They also made arrangements such as purchase of food, drinking water, medicines, etc., for home but also for office as well. Even though most of them were initially excited about the lockdown it was then followed by fear of contracting the disease, worries about loss of work and financial security. The study participants identified the advantages of lockdown as having more time for self & for family, use of the online/digital medium for routine activities and many also appreciated the support provided by the government in the form of food kits and loans. The lockdown was found to have increased the workload especially for women who had to manage not only family but also online work from home. Conclusion: The study was able to capture the different experiences and challenges faced by the middle-class working population. Even though they went through a cascade of initial excitement followed by fear of contracting the disease, it eventually turned into concerns of job and financial insecurities. The united frontline work of various sectors like police, health sector, local self-government, Kudumbashree and voluntary groups collectively aided in building community resilience enabling the southern state of Kerala to overcome the devastating effects of the pandemic and lockdown.